Principal Scientist, Computational Image Analysis

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: March 13, 2026

Job Description:

The Computational Image Analysis team is seeking a motivated data scientist who is passionate about biological applications of imaging. Our team develops rigorous analytical methods for image quantification to support cutting-edge biopharmaceutical research, working collaboratively within Regenerons Imaging Sciences department and with diverse teams throughout the company. We are hiring a Principal Scientist to architect high-impact, deep learning-powered image processing pipelines, deliver validated quantitative results, and contribute to data management strategy for imaging datasets of multiple modalities. Working at the intersection of science and technology, you'll build cross-functional relationships with researchers across therapeutic areas and coordinate with IT partners to enhance research capabilities. In this role, a typical day may include: Defining quantitative imaging endpoints and biomarkers to meet the experimental goals of our collaborators Leading development and validation of image processing pipelines to analyze biomedical images of various modalities, including microscopy, histology, ultrasound, PET/CT, and MRI Executing image analysis workflows to generate quantitative results and creating advanced visualizations to facilitate interpretation Preparing deliverables to disseminate analytical results, ensuring methods and findings are clearly communicated and documented Playing a crucial role in data annotation and quality control to ensure the integrity and reliability of our research data Actively participating in cross-functional meetings, including presentation of analytical plans, methods, and results Contributing to data management efforts, guided by FAIR principles, to maintain data integrity and accelerate scientific insights This role may be for you if: You have outstanding critical thinking, attention to detail, scientific rigor, and strong analytical, problem solving, and troubleshooting skills You have a demonstrated ability to work independently and collaboratively as part of a larger project You are a highly effective communicator who can interface with both biologists and IT professionals to translate scientific needs into analytical endpoints You have a positive demeanor and willingness to grow, learn, and adapt in a fast-paced research environment You have a passion for biology, and a dedication to share, collaborate, and lift up others To be considered for this role candidates must hold an advanced degree in Computer Science, Biomedical Engineering, Mathematics, or a related field (PhD with 6 years of relevant work experience). Candidates should demonstrate the ability to understand scientific questions in the context of drug development. Proficiency in Python programming and a solid understanding of computer science fundamentals is required, including experience with version control and AI coding assistants such as Claude Code. They should possess a strong understanding of modern image processing principles, including deep learning-based approaches. Expertise in mathematics relevant to quantitative image analysis (e.g., optimization, regression, statistics, signal processing, cluster analysis, machine learning) is highly desirable. Experience developing custom analysis pipelines in an enterprise AI platform such as Dataiku and knowledge of distributed computing frameworks (e.g., PySpark) is preferred. The ideal candidate will have familiarity with a range of third-party software tools for biomedical image analysis (e.g., HALO, Imaris, 3D Slicer). Familiarity with data annotation workflows (e.g., using v7 Darwin), data management platforms (e.g., PathCore, HALO Link, Flywheel), and relevant APIs/CLIs are preferred. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regenerons roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regenerons on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $128,600.00 - $210,000.00

Keywords: Regeneron Pharmaceuticals, Inc., West Hartford , Principal Scientist, Computational Image Analysis, Science, Research & Development , Tarrytown, Connecticut